Study summary

The purpose of this study was to evaluate the efficacy of postsurgery treatment with ASP1128 in subjects at risk for AKI following CABG and/or valve surgery.

This study also investigated the safety and tolerability of postsurgery treatment with ASP1128, and pharmacokinetic characteristics of ASP1128 in subjects at risk for AKI following CABG and/or valve surgery.

Additional Study Details

Phase
Phase 2
Product
  • ASP1128
  • Placebo
  • Type
    Interventional
    Masking
    Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
    Enrollment number
    351
    Show Additional Study Details

    Study documents

    Scientific Results Summary
    Available Language(s): English
    Plain Language Summary
    Available Language(s): English
    Protocol
    Available Language(s): English
    Statistical Analysis Plan (SAP)
    Available Language(s): English

    Get more information

    Would you like more information about clinical trial sites that are recruiting participants for Study to Evaluate the Efficacy of ASP1128 (MA-0217) in Subjects at Risk for Acute Kidney Injury (AKI) following Coronary Artery Bypass Graft (CABG) and/or Valve Surgery? Contact us by filling out your information to the right and we’ll respond to you.

    • A patient
    • A caregiver
    • A parent
    • A healthcare provider
    • A patient advocate
    • Algeria
    • Argentina
    • Armenia
    • Australia
    • Austria
    • Belarus
    • Belgium
    • Bosnia And Herzegovina
    • Brazil
    • Bulgaria
    • Canada
    • Chile
    • China
    • Colombia
    • Croatia
    • Czech Republic
    • Denmark
    • Dominican Republic
    • Egypt
    • Estonia
    • Finland
    • Former Serbia and Montenegro
    • France
    • Georgia
    • Germany
    • Greece
    • Guatemala
    • Hong Kong
    • Hungary
    • Iceland
    • India
    • Indonesia
    • Ireland
    • Israel
    • Italy
    • Japan
    • Jordan
    • Kazakhstan
    • Latvia
    • Lebanon
    • Lithuania
    • Macedonia
    • Malaysia
    • Mexico
    • Montenegro
    • Morocco
    • Netherlands
    • New Zealand
    • Norway
    • Panama
    • Peru
    • Philippines
    • Poland
    • Portugal
    • Puerto Rico
    • Republic of Korea
    • Republic of Moldova
    • Romania
    • Russian Federation
    • Saudi Arabia
    • Serbia
    • Singapore
    • Slovakia
    • Slovenia
    • South Africa
    • Spain
    • Sweden
    • Switzerland
    • Taiwan, Province of China
    • Thailand
    • Turkey
    • Ukraine
    • United Kingdom
    • United States
    • Vietnam

    By clicking ["Continue/Submit"], you agree that Astellas may contact you by email with information to help you connect with clinical trial sites. While we can connect you to clinical trial sites, we cannot answer questions about any investigational therapy through email. Your consent to receiving emails is not a requirement to participate in a clinical trial or study. For more information, including how to unsubscribe at any time, see our Privacy Notice & Cookies Policy.

      Locations

      Contact Us
      Contact Us
      Withdrawn
      Keck School of Medicine USC
      Los Angeles, CA, United States, 90033
      Completed
      ProMedica Toledo Hospital
      Toledo, OH, United States, 43606
      Completed
      Sarver Heart Center
      Tucson, AZ, United States, 85724
      Completed
      Baylor Scott & White Heart Hospital
      Plano, TX, United States, 75093
      Completed
      Florida Hospital Pepin Heart Institute
      Tampa, FL, United States, 33613
      Completed
      Indiana University Health Ball Memorial Hospital
      Muncie, IN, United States, 47303
      Completed
      Delmarva Heart, LLC
      Salisbury, MD, United States, 21804
      Completed
      WVU Heart and Vascular Institute
      Morgantown, WV, United States, 26506
      Completed
      St. Vincent Heart Center
      Indianapolis, IN, United States, 46290
      Completed
      Minneapolis Heart Institute
      Minneapolis, MN, United States, 55407
      Completed
      Ascension Genesys Hospital
      Grand Blanc, MI, United States, 48439
      Withdrawn
      JEHM clinical Research Group
      Palm Springs, CA, United States, 92262
      Completed
      Fairview Hospital - Cleveland Clinic
      Cleveland, OH, United States, 44111
      Withdrawn
      Maine Medical Center
      Portland, ME, United States, 04102
      Withdrawn
      Inova Heart and Vascular Institute
      Falls Church, VA, United States, 22042
      Completed
      University of Texas Health Science Center
      San Antonio, TX, United States, 78229
      Withdrawn
      VA Medical Center
      Washington, DC, United States, 20422
      Completed
      Health Park Medical Center
      Fort Myers, FL, United States, 33908
      Withdrawn
      University of Florida- Jacksonville
      Jacksonville, FL, United States, 32209
      Completed
      Baptist Medical Center
      Jackson, MS, United States, 39202
      Withdrawn
      Medical City Dallas Hospital
      Dallas, TX, United States, 75230
      Completed
      Southern Illinois University
      Springfield, IL, United States, 62794
      Completed
      Vanderbilt University
      Nashville, TN, United States, 37232
      Completed
      Shands Hospital
      Gainesville, FL, United States, 32610
      Completed
      IU Health - Methodist
      Indianapolis, IN, United States, 46202
      Completed
      Duke University Medical Center
      Durham, NC, United States, 27710
      Completed
      Luthern Medical Group
      Fort Wayne, IN, United States, 46804
      Withdrawn
      Barnes Jewish Hospital
      St. Louis, MO, United States, 63110
      Completed
      Lourdes Cardiology Services
      Voorhees, NJ, United States, 08035
      Withdrawn
      Hartford Hospital
      Hartford, CT, United States, 06102
      Withdrawn
      Jacksonville Center for Clinical Research
      Jacksonville, FL, United States, 32207
      Completed
      Heart Center Research, LLC
      Huntsville, AL, United States, 35801
      Completed
      Morton Plant Hospital
      Clearwater, FL, United States, 33756
      Completed
      Moses H. Cone Memorial Hospital
      Greensboro, NC, United States, 27401
      Completed
      Mid Michigan Medical Center
      Midland, MI, United States, 48670
      Withdrawn
      University Hospitals - Cleveland Medical Center
      Cleveland, OH, United States, 44106
      Completed
      MercyOne Iowa Heart Center
      Des Moines, IA, United States, 50314
      Withdrawn
      University of Utah Hospitals and Clinics
      Salt Lake City, UT, United States, 84132
      Withdrawn
      University of Oklahoma
      Oklahoma City, OK, United States, 73104
      Withdrawn
      University of Virginia Health System
      Charlottesville, VA, United States, 22908
      Completed
      St. Luke's Hospital of Kansas City
      Kansas City, MO, United States, 64111
      Withdrawn
      Columbia University Irving Medical Center
      New York, NY, United States, 10032
      Withdrawn
      Medical University of South Carolina
      Charleston, SC, United States, 29425
      Withdrawn
      Temple University Hospital
      Philadelphia, PA, United States, 19140
      Withdrawn
      Suburban Hospital Inc
      Bethesda, MD, United States, 20814

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