Study summary

This study was conducted to explore a new therapy for anemia in participants with end stage renal disease (ESRD) on dialysis. Anemia is a reduced number of red blood cells or hemoglobin. Hemoglobin (which contains iron) is important for the transport of oxygen in your blood. The purpose of this study was to evaluate if roxadustat is effective and safe in the maintenance treatment of anemia in ESRD participants on stable dialysis. Roxadustat was compared to epoetin alfa and darbepoetin alfa, commercially available medicines for treatment of anemia.

Additional Study Details

Phase
3
Product
ASP1517
Product
Roxadustat
Epoetin alfa
Darbepoetin alfa
Iron
Type
Interventional
Masking
None (Open Label)
Enrollment number
838
Show Additional Study Details

Study documents

Scientific Results Summary
Available Language(s): English
Plain Language Summary
Available Language(s): English
Protocol
Available Language(s): English
Statistical Analysis Plan (SAP)
Available Language(s): English

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Would you like more information about clinical trial sites that are recruiting participants for Roxadustat in the Treatment of Anemia in End Stage Renal Disease (ESRD) Patients on Stable Dialysis? Contact us by filling out your information to the right and we’ll respond to you.

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    Locations

    Contact Us
    Contact Us
    Withdrawn
    Site HU36007
    Budapest, Hungary, H 1115
    Completed
    Site GB44001
    Swansea, United Kingdom, SA6 6NL
    Completed
    Site GB44081
    Leicester, United Kingdom, LE5 4PW
    Completed
    Site ES34002
    Badalona-Barcelona, Spain, 8916
    Completed
    Site ES34030
    Majadahonda, Madrid, Spain, 28222
    Completed
    Site BE32004
    Brussels, Flemish Brabant, Belgium, 1200
    Withdrawn
    Site FR33050
    Angers, France, 49033
    Completed
    Site RU70005
    Moscow, Russian Federation, 125284
    Terminated
    Site PT35139
    Cascais, Portugal, 2750-663
    Withdrawn
    Site ES34035
    Barcelona, Barcelona, Spain, 08036
    Completed
    Site PT35127
    Aveiro, Portugal, 3800-266
    Completed
    Site RS38105
    Belgrade, Serbia, 11000
    Completed
    Site ES34011
    Galdakao, Vizcaya, Spain, 48960
    Completed
    Site PT35121
    Almada, Portugal, 2800-455
    Completed
    Site RS38117
    Krusevac, Serbia, 37000
    Completed
    Site RO40015
    Bucharest, Romania
    Completed
    Site RO40004
    Oradea, Romania, 410562
    Completed
    Site BG35919
    Plovdiv, Plovdiv, Bulgaria, 4003
    Terminated
    Site BE32017
    Bonheiden, Belgium, 2820
    Terminated
    Site ES34008
    Barcelona, Barcelona, Spain, 08025
    Terminated
    Site HU36046
    Szekesfehervar, Hungary, 8000
    Terminated
    Site HR38508
    Cakovec, Croatia, 40000
    Completed
    Site BE32003
    Leuven, Belgium, 3000
    Completed
    Site HU36026
    Kaposvar, Hungary, H 7400
    Withdrawn
    Site PL48004
    Warszawa, Poland, 04 749
    Terminated
    Site GB44079
    Liverpool, United Kingdom, L9 7AL
    Completed
    Site SK42119
    Levice, Slovakia, 93401
    Terminated
    Site HR38501
    Zadar, Croatia, 23 000
    Withdrawn
    Site DE49049
    Trier, Germany, 54292
    Completed
    Site HR38504
    Slavonski Brod, Croatia, 35000
    Completed
    Site RS38104
    Belgrade, Serbia
    Completed
    Site RU70037
    Volgograd, Russian Federation, 404120
    Completed
    Site BG35907
    Stara Zagora, Bulgaria, 6000
    Completed
    Site BG35916
    Varna, Bulgaria, 9000
    Completed
    Site IT39032
    Trieste, Italy, 34142
    Completed
    Site DE49073
    Cloppenburg, Germany, 49661
    Completed
    Site DE49054
    Dusseldorf, Germany, 40210
    Completed
    Site RO40018
    Bucharest, Romania, 011794
    Completed
    Site SK42102
    Koshice, Slovakia, 04001
    Withdrawn
    Site FR33063
    Quincy sous Senart, France, 91480
    Completed
    Site BE32002
    Antwerp, Belgium, 2060
    Terminated
    Site GE99503
    Tbilisi, Georgia, 0144
    Completed
    Site ES34009
    El Ejido, Almeria, Spain, 04700
    Completed
    Site SK42113
    Puchov, Slovakia, 020 01
    Terminated
    Site IT39010
    Brescia, Italy, 25123
    Completed
    Site BG35920
    Rousse, Bulgaria, 7002
    Completed
    Site BE32011
    Roeselare, Belgium, 8800
    Completed
    Site BG35906
    Sofia, Bulgaria, 1431
    Completed
    Site RU70014
    Rostov-on-Don, Russian Federation, 344029
    Terminated
    Site ES34010
    Alcorcon, Madrid, Spain, 28922
    Terminated
    Site DE49002
    Solingen, Germany, 42653
    Completed
    Site PT35128
    Gaeiras, Portugal, 2510-702
    Completed
    Site IT39008
    Lecco, Italy, 23900
    Completed
    Site ES34041
    Santiago de Compostela, A Coruna, Spain, 15706
    Completed
    Site FR33055
    Saint Ouen, France, 93400
    Completed
    Site RS38102
    Belgrade, Serbia, 11000
    Completed
    Site PT35114
    Leiria, Portugal, 2400-441
    Withdrawn
    Site PT35120
    Almada, Portugal, 2801-951
    Withdrawn
    Site RU70073
    Nizhniy Novgorod, Russian Federation, 603126
    Completed
    Site PL48013
    Szczecin, Poland, 70-111
    Withdrawn
    Site FR33008
    Nantes Cedex 1, France, 44093
    Withdrawn
    Site RO40020
    Odorheiu Secuiesc, Harghita, Romania, 535600
    Completed
    Site DE49070
    Muenchen, Germany, 81695
    Completed
    Site SK42120
    Lučenec, Slovakia, 984 01
    Completed
    Site RU70050
    Saint-Petersburg, Russian Federation, 197374
    Completed
    Site FR33010
    La Tronche, France, 38701
    Completed
    Site BG35924
    Sofia, Bulgaria, 1309
    Withdrawn
    Site DE49072
    Herne, Germany, 44626
    Withdrawn
    Site IT39040
    San Fermodella Battaglia, Como, Italy, 22020
    Withdrawn
    Site PT35140
    Corroios, Portugal, 2855 -227
    Completed
    Site RU70008
    Kaluga, Russian Federation, 248007
    Completed
    Site ES34017
    Jaen, Jaen, Spain, 23007
    Completed
    Site PT35117
    Faro, Portugal, 8005-546
    Terminated
    Site PL48009
    Wroclaw, Poland, 51 124
    Completed
    Site IT39028
    Prato, Frazione di Galciana, Italy, 59100
    Completed
    Site RS38101
    Nis, Serbia
    Completed
    Site RU70030
    Sankt-Peterburg, Russian Federation, 197110
    Completed
    Site CZ42015
    Rakovnik, Czech Republic, 26929
    Withdrawn
    Site ES34039
    Cordoba, Cordoba, Spain, 14004
    Completed
    Site BG35921
    Sofia, Bulgaria, 1527
    Completed
    Site BG35903
    Veliko Tarnovo, Bulgaria, 5000
    Completed
    Site HU36006
    Szombathely, Hungary, H 9700
    Terminated
    Site BG35909
    Plovdiv, Bulgaria, 4000
    Completed
    Site PL48014
    Zamosc, Poland, 20-400
    Terminated
    Site BE32019
    Antwerpen, Belgium, 2020
    Terminated
    Site GB44080
    Stoke on Trent, Staffordshire, United Kingdom, ST4 6QG
    Completed
    Site RU70011
    Saint-Petersburg, Russian Federation, 196247
    Completed
    Site CZ42008
    Liberec, Czech Republic, 46063
    Withdrawn
    Site RS38103
    Belgrade, Serbia, 11080
    Completed
    Site HU36027
    Kistarcsa, Hungary, 2143
    Terminated
    Site ES34037
    Madrid, Madrid, Spain, 28046
    Withdrawn
    Site BG35923
    Pazardjik, Bulgaria
    Completed
    Site BG35915
    Pleven, Bulgaria, 5800
    Completed
    Site RU70002
    Saint Petersburg, Russian Federation, 197089
    Completed
    Site HU36003
    Zalsaegerszeg, Hungary, 8900
    Completed
    Site IT39006
    Milano, Italy, 20162
    Completed
    Site HU36036
    Esztergom, Hungary, 2500
    Completed
    Site BG35918
    Varna, Bulgaria, 9010
    Completed
    Site IT39022
    Padova, Italy, 35128
    Terminated
    Site RU70051
    Moscow, Russian Federation, 119992
    Completed
    Site IT39036
    Pavia, Italy, 27100
    Completed
    Site HU36004
    Szeged, Hungary, 6724
    Completed
    Site BE32013
    Liege, Belgium, 4000
    Completed
    Site RS38116
    Zrenjanin, Serbia
    Completed
    Site RO40003
    Bucuresti, Romania, 22328
    Completed
    Site BG35925
    Blagoevgrad, Bulgaria, 2700
    Completed
    Site RU70004
    Omsk, Russian Federation, 644112
    Completed
    Site IT39035
    Torino, Italy, 10126
    Completed
    Site RU70001
    Yaroslavl, Russian Federation, 150062
    Completed
    Site DE49071
    Villingen-Schwenningen, Germany, 78052
    Completed
    Site FR33007
    St Priez en Jarez, France, 42270
    Withdrawn
    Site FR33057
    Le Mans, France, 72037
    Completed
    Site ES34052
    Valencia, Valencia, Spain, 46017
    Terminated
    Site RU70006
    Smolensk, Russian Federation, 214006
    Withdrawn
    Site GB44007
    London, United Kingdom, SM5 1AA
    Withdrawn
    Site DE49031
    Bonn, Germany, 53127
    Terminated
    Site FR33005
    Amiens cedex 1, France, 80054
    Completed
    Site IT39039
    Cremona, Lombardia, Italy, 26100
    Withdrawn
    Site FR33009
    Colmar Cedex, France, 68024
    Completed
    Site IT39014
    Mestre, Venezia, Italy, 30174
    Completed
    Site PL48006
    Wroclaw, Poland, 50-556
    Terminated
    Site DE49008
    Dresden, Germany, 01307
    Completed
    Site HU36035
    Pecs, Hungary, 7633
    Completed
    Site HU36032
    Pecs, Hungary, 7624
    Completed
    Site BG35938
    Shumen, Bulgaria, 9700
    Completed
    Site HR38506
    Rijeka, Croatia, 51000
    Completed
    Site PL48001
    Krakow, Poland, 30 501
    Withdrawn
    Site ES34001
    Bilbao, Bizkaia, Spain, 48013
    Completed
    Site RU70072
    Saint Petersburg, Russian Federation, 190103
    Terminated
    Site PL48002
    Katowice, Poland, 40 027
    Completed
    Site GB44087
    Brighton, EastSussex, United Kingdom, BN2 5BD
    Completed
    Site SK42116
    Senica, Slovakia, 90501
    Terminated
    Site PT35102
    Porto, Portugal, 4099-001
    Completed
    Site RU70003
    Nizhny Novgorod, Russian Federation, 603032
    Completed
    Site BG35931
    Haskovo, Bulgaria, 6300
    Completed
    Site RS38120
    Belgrade, Serbia, 11000
    Completed
    Site DE49067
    Berlin, Germany, 10117
    Withdrawn
    Site FR33004
    Avignon, France, 84900
    Withdrawn
    Site GB44077
    Portsmouth, United Kingdom, PO63LY
    Terminated
    Site HU36034
    Salgotarjan, Hungary, 3100
    Completed
    Site HU36031
    Gyor, Hungary, 9002
    Completed
    Site RO40019
    Bucharest, Romania
    Completed
    Site FR33056
    Valenciennes, France, 59300
    Completed
    Site GB44011
    Canterbury, Kent, United Kingdom, CT1 3NG
    Completed
    Site GB44010
    Hull, United Kingdom, HU3 2JZ
    Completed
    Site PT35122
    Setubal, Portugal, 2900-655
    Terminated
    Site BE32012
    Baudour, Belgium, 7331
    Terminated
    Site PL48005
    Warszawa, Poland, 00 507
    Completed
    Site GE99504
    Tbilisi, Georgia, 0144
    Completed
    Site HR38505
    Karlovac, Croatia, 47000
    Terminated
    Site IT39005
    Roma, Italy, 122
    Terminated
    Site ES34006
    Barcelona, Barcelona, Spain, 08035
    Completed
    Site HU36033
    Baja, Hungary, 6500
    Completed
    Site DE49075
    Heilbronn, Germany, 74076
    Completed
    Site GE99508
    Tbilisi, Georgia, 159
    Completed
    Site DE49056
    Dormagen, Nordrhein-Westfalen, Germany, 41540
    Completed
    Site CZ42021
    Praha 6, Czech Republic, 169 00
    Withdrawn
    Site FR33001
    Creteil, France, 94010
    Completed
    Site HR38507
    Osijek, Croatia, 31 000
    Completed
    Site BG35937
    Yambol, Bulgaria, 8600
    Completed
    Site GB44008
    Cambridge, United Kingdom, CB2 0QQ
    Terminated
    Site DE49001
    Kaiserslautern, Germany, 67655
    Completed
    Site HR38509
    Zagreb, Grad Zagreb, Croatia, 10000
    Completed
    Site DE49020
    Frankfurt am Main, Germany, 60590
    Completed
    Site BE32001
    Aalst, Belgium, 9300
    Completed
    Site DE49065
    Hamburg, Germany, 23397
    Completed
    Site IT39037
    Modena, Italy, 41124

    Frequently Asked Questions

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