Study Details

A Study of ASP1948, Targeting an Immune Modulatory Receptor as a Single Agent and in Combination With a PD-l Inhibitor (Nivolumab or Pembrolizumab) in Subjects With Advanced Solid Tumors

This trial is complete
The study has ended normally, and participants are no longer being examined or treated (that is, the last participant's last visit has occurred).

Clinicaltrials.gov ID

The unique identification code given to each clinical study upon registration at ClinicalTrials.gov.
NCT03565445

Astellas Study ID

The unique identification code given by the study sponsor.

1948-CL-0101

EudraCT ID

The unique identification code given to each clinical study upon registration at EudraCT (European Union Drug Regulating Authorities Clinical Trials Database).

2018-003873-82

Condition

Advanced/Metastatic Cancer

Phase

These clinical trials are usually the first time an experimental treatment is studied in a small group of people.

Phase 1

Age

18 Years - N/A

Sex

Female & Male

Product

ASP1948

Type

A type of clinical study in which participants are assigned to groups that receive one or more intervention/treatment (or no intervention) so that researchers can evaluate the effects of the interventions on biomedical or health-related outcomes.

Interventional

Trial Dates

Jul 2018 - Mar 2023

Masking

None (Open Label)

Enrollment number

190

A Phase 1b Study of ASP1948, Targeting an Immune Modulatory Receptor as a Single Agent and in Combination with a PD-l inhibitor (Nivolumab or Pembrolizumab) in Subjects with Advanced Solid Tumors

Study summary

Get More Information

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Locations

Norton Cancer Institute

Louisville, United States, 40202

Site TW88602

Taipei, Taiwan, Province of China

Oncology Hematology West P.C. dba Nebraska Cancer Specialists

Omaha, United States, 68310

Site KR82002

Seoul, Republic of Korea

Washington University

St. Louis, United States, 63110

University of Chicago

Chicago, United States, 60637

Site KR82005

Seoul, Republic of Korea

Mary Crowley Cancer Research Center

Dallas, United States, 75230

Site KR82004

Seoul, Republic of Korea

Comprehensive Cancer Centers of Nevada

Las Vegas, United States, 89169

University of Tennessee Medical Center

Knoxville, United States, 37920

Montefiore Medical Center

Bronx, United States, 10461

Virginia Cancer Care Specialist, PC

Fairfax, United States, 22031

Henry-Joyce Cancer Center

Nashville, United States, 37232

Site CA15001

Toronto, Canada

Memorial Sloan Kettering Cancer Center

New York, United States, 10065

Cancer Center at Greater Baltimore Medical

Baltimore, United States, 21153

University of Washington-Seattle Cancer Care Alliance

Seattle, United States, 98109

Icahn School of Medicine at Mount Sinai

New York, United States, 10029

Site KR82001

Seoul, Republic of Korea

Site CA15004

Montreal, Canada

University of Oklahoma

Oklahoma City, United States, 73104

University of Michigan Comprehensive Cancer Center

Ann Arbor, United States, 48109

Sarah Cannon Research Institute – SCRI

Nashville, United States, 37203

Froedtert & The medical college of Wisconsin

Milwaukee, United States, 53226

Oregon Health and Science University

Portland, United States, 97239

The Ohio State University James Cancer Hospital and Solove Research Institute

Columbus, United States, 43210

Site KR82006

Seoul, Republic of Korea

Site KR82003

Seoul, Republic of Korea

Yale Center for Clinical Investigation

New Haven, United States, 06520-8028

Augusta University

Augusta, United States, 30912

UPMC- Hillman Cancer Center

Pittsburgh, United States, 15232

Site KR82007

Seoul, Republic of Korea

University of South Carolina

Charleston, United States, 29425

Dartmouth Hitchcock Med Center

Lebanon, United States, 03756

South Texas Accelerated Research Therapeutics

San Antonio, United States, 78229

Site CA15002

Edmonton, Canada

Women And Infants

Providence, United States, 02905

Site ES34001

Avila, Spain

Site ES34003

Cataluna, Spain

Site ES34004

Cataluna, Spain

Site ES34005

Valencia, Spain

Site ES34007

Madrid, Spain

Site ES34009

Madrid, Spain

Site ES34012

Madrid, Spain

Site GB44001

Glasgow, United Kingdom

Site TW88601

Taipei, Taiwan, Province of China

Site ES34010

Barcelona, Spain

Site JP81001

Tokyo, Japan

Site JP81002

Chiba, Japan

Site IT39006

Modena, Italy

Site IT39008

Milano, Italy

Site IT39003

Meldola, Italy

Site ES34002

Barcelona, Spain

Huntsman Cancer Institute

Salt Lake City, United States, 84112

Site ES34006

Barcelona, Spain

Site ES34014

Barcelona, Spain

Site CA15006

Toronto, Canada

Site IT39001

Monza, Italy

Site IT39005

Milano, Italy

Site IT39007

Milano, Italy

Site PT35104

Porto, Portugal

Site PT35105

Braga, Portugal

Site GB44003

Sheffield, United Kingdom

Site GB44004

Newcastle upon Tyne, United Kingdom

Site GB44006

Manchester, United Kingdom

Mayo clinic

Phoenix, United States, 85259

Site TW88603

Tainan, Taiwan, Province of China

Henry Ford Health System

Detroit, United States, 48202