Study summary

The purpose of this study was to evaluate the efficacy of enzalutamide with trastuzumab in patients with HER2+ AR+ metastatic or locally advanced breast cancer.

Additional Study Details

Phase
Phase 2
Product
  • Enzalutamide
  • Trastuzumab
  • Type
    Interventional
    Masking
    None (Open Label)
    Enrollment number
    103
    Show Additional Study Details

    Study documents

    Scientific Results Summary
    Available Language(s): English
    Plain Language Summary
    Available Language(s): English
    Protocol
    Available Language(s): English
    Statistical Analysis Plan (SAP)
    Available Language(s): English

    Get more information

    Would you like more information about clinical trial sites that are recruiting participants for A Study to Assess the Efficacy and Safety of Enzalutamide with Trastuzumab in Patients with Human Epidermal Growth Factor Receptor 2 Positive (HER2+), Androgen Receptor Positive (AR+) Metastatic or Locally Advanced Breast Cancer? Contact us by filling out your information to the right and we’ll respond to you.

    • A patient
    • A caregiver
    • A parent
    • A healthcare provider
    • A patient advocate
    • Algeria
    • Argentina
    • Armenia
    • Australia
    • Austria
    • Belarus
    • Belgium
    • Bosnia And Herzegovina
    • Brazil
    • Bulgaria
    • Canada
    • Chile
    • China
    • Colombia
    • Croatia
    • Czech Republic
    • Denmark
    • Dominican Republic
    • Egypt
    • Estonia
    • Finland
    • Former Serbia and Montenegro
    • France
    • Georgia
    • Germany
    • Greece
    • Guatemala
    • Hong Kong
    • Hungary
    • Iceland
    • India
    • Indonesia
    • Ireland
    • Israel
    • Italy
    • Japan
    • Jordan
    • Kazakhstan
    • Latvia
    • Lebanon
    • Lithuania
    • Macedonia
    • Malaysia
    • Mexico
    • Montenegro
    • Morocco
    • Netherlands
    • New Zealand
    • Norway
    • Panama
    • Peru
    • Philippines
    • Poland
    • Portugal
    • Puerto Rico
    • Republic of Korea
    • Republic of Moldova
    • Romania
    • Russian Federation
    • Saudi Arabia
    • Serbia
    • Singapore
    • Slovakia
    • Slovenia
    • South Africa
    • Spain
    • Sweden
    • Switzerland
    • Taiwan, Province of China
    • Thailand
    • Turkey
    • Ukraine
    • United Kingdom
    • United States
    • Vietnam

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      Locations

      Contact Us
      Contact Us
      Withdrawn
      Site US10002
      Aurora, CO, United States, 80045
      Completed
      Site GB44013
      Manchester, United Kingdom, M20 4BX
      Withdrawn
      Site US10080
      Whittier, CA, United States, 90603
      Completed
      Site US10042
      Nashville, TN, United States, 37203
      Completed
      Site IT39003
      Milan, Italy, 20132
      Withdrawn
      Site US10031
      Houston, TX, United States, 77030
      Completed
      Site BE32001
      Charleroi, Belgium, 6000
      Completed
      Site IT39002
      Milano, Italy, 20141
      Completed
      Site US10074
      Gainsville, FL, United States, 32605
      Completed
      Site US10077
      Nashville, TN, United States, 37232
      Completed
      Site IT39021
      Udine, Italy, 33100
      Completed
      Site BE32003
      Edegem, Antwerp, Belgium, 2650
      Completed
      Site ES34014
      Pozuelo de Alarcon, Madrid, Spain, 28223
      Withdrawn
      Site US10021
      Chicago, IL, United States, 60611-5975
      Completed
      Site IT39005
      Meldola, Forli, Italy, 47014
      Withdrawn
      Site CA15025
      Montreal, Quebec, Canada, H4A 3J1
      Completed
      Site GB44003
      Edinburgh, United Kingdom, EH4 2XU
      Withdrawn
      Site ES34001
      Lleida, Spain, 25198
      Completed
      Site US10051
      Anaheim, CA, United States, 92801
      Completed
      Site BE32013
      Brasschaat, Belgium, 2930
      Completed
      Site US10076
      Fort Worth, TX, United States, 76104
      Withdrawn
      Site CA15027
      Sault Ste Marie, ON, Canada, P6B 0A8
      Completed
      Site ES34010
      Barcelona, Barcelona, Spain, 08035
      Withdrawn
      Site US10001
      Los Angeles, CA, United States, 90033
      Completed
      Site US10078
      St. Louis, MO, United States, 63110
      Completed
      Site IT39008
      Lecce, Italy, 73100
      Completed
      Site US10028
      Los Angeles, CA, United States, 90048
      Completed
      Site GB44001
      Nottingham, United Kingdom, NG5 1PB
      Completed
      Site BE32009
      Leuven, Belgium, 3000
      Completed
      Site US10081
      Chicago, IL, United States, 60637
      Completed
      Site US10079
      Fort Myers, FL, United States, 33916
      Completed
      Site BE32016
      Bruxelles, Belgium, 1200
      Completed
      Site US10035
      San Francisco, CA, United States, 94115
      Completed
      Site ES34013
      Madrid, Madrid, Spain, 28050
      Completed
      Site CA15023
      Toronto, ON, Canada, M4N 3M5
      Withdrawn
      Site US10027
      Burbank, CA, United States, 91505
      Completed
      Site US10070
      Boston, MA, United States, 02215
      Completed
      Site BE32007
      Liege, Belgium, 4000
      Completed
      Site US10072
      Cincinnati, OH, United States, 45242
      Withdrawn
      Site BE32017
      Gent, Belgium, 9000
      Completed
      Site CA15026
      Saskatoon, SK, Canada, S7N 4H4
      Completed
      Site CA15001
      Quebec, Quebec, Canada, G1S 4L8
      Completed
      Site IT39001
      Sondrio, Italy, 23100
      Completed
      Site CA15028
      Regina, SK, Canada, S4T7T1
      Withdrawn
      Site CA15015
      Edmonton, AB, Canada, T6G 1Z2
      Withdrawn
      Site CA15029
      Montreal, Quebec, Canada, H3G 1L5
      Completed
      Site US10082
      Houston, TX, United States, 77030
      Completed
      Site CA15022
      Ottawa, ON, Canada, K1H 8L6
      Completed
      Site US10029
      Knoxville, TN, United States, 37909
      Completed
      Site US10048
      Pittsburgh, PA, United States, 15213
      Withdrawn
      Site GB44011
      Leeds, United Kingdom, LS7 9TF
      Completed
      Site US10004
      Indianapolis, IN, United States, 46202

      Frequently Asked Questions

      Are clinical trials only for people with advanced cancer?

      While some clinical trials may focus on more advanced cancers, many trials are open to patients at various stages of their cancer. Each study has rules about who can take part. For example, only patients in a certain age group or those who have a certain type of tumor may be able to join.

      Will I have to stop my current treatment to participate in a clinical trial?

      Sometimes researchers want participants to keep taking their current treatments during a clinical trial. Other times, you may need to stop your current treatments for a while. If the investigational treatment doesn't work, you can usually go back to your original treatment plan.

      Should I be worried about getting a placebo?

      In cancer clinical trials, a placebo is only used if there is no other treatment for that type of cancer. This helps compare an investigational treatment to the placebo. Placebos are rarely used in cancer trials because the best available treatment, called the “standard of care”, is usually given instead.

      Do I need a referral from my doctor to take part in a study?

      Your doctor may not know about all the opportunities for clinical trials that are available to you. Talk to your doctor or other medical provider about clinical trial information that you find. They can help you decide if a clinical trial is right for you. If you do not find any options on this website, we recommend you visit an online public registry website like clinicaltrials.gov to see a wide variety of available clinical trials.

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