Study summary

The purpose of the study was to understand if there was benefit in continued treatment with a medicine called enzalutamide, when starting treatment with docetaxel and prednisolone (a standard chemotherapy for prostate cancer), after the prostate cancer had gotten worse when treated with enzalutamide alone.

Additional Study Details

Phase
Phase 3
Product
  • Enzalutamide
  • Docetaxel
  • Prednisolone
  • Placebo
  • Type
    Interventional
    Masking
    Triple (Participant, Investigator, Outcomes Assessor)
    Enrollment number
    688
    Show Additional Study Details

    Study documents

    Scientific Results Summary 2
    Available Language(s): English
    Plain Language Summary
    Available Language(s): English
    Protocol
    Available Language(s): English
    Statistical Analysis Plan (SAP)
    Available Language(s): English

    Get more information

    Would you like more information about clinical trial sites that are recruiting participants for A Study to Assess the Benefit of Treatment Beyond Progression With Enzalutamide in Men Who Are Starting Treatment With Docetaxel After Worsening of Their Prostate Cancer When Taking Enzalutamide Alone? Contact us by filling out your information to the right and we’ll respond to you.

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    • Argentina
    • Armenia
    • Australia
    • Austria
    • Belarus
    • Belgium
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    • Brazil
    • Bulgaria
    • Canada
    • Chile
    • China
    • Colombia
    • Croatia
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    • Denmark
    • Dominican Republic
    • Egypt
    • Estonia
    • Finland
    • Former Serbia and Montenegro
    • France
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    • Germany
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      Locations

      Contact Us
      Contact Us
      Completed
      Site NO47004
      Stavanger, Norway, 4011
      Completed
      Site SE46004
      Uppsala, Sweden, 751 85
      Withdrawn
      Site BE32005
      Turnhout, Belgium, 2300
      Completed
      Site ES34007
      Malaga, Spain, 29010
      Completed
      Site RU70003
      Moscow, Russian Federation, 125284
      Completed
      Site RU70001
      Moscow, Russian Federation, 115478
      Completed
      Site GB44002
      Nottingham, United Kingdom, NG5 1PB
      Completed
      Site GB44004
      Cambridge, United Kingdom, CB2 0QQ
      Completed
      Site TR90003
      Istanbul, Turkey, 34722
      Completed
      Site ES34006
      Valencia, Spain, 46009
      Completed
      Site DE49004
      Wuppertal, Germany, 42103
      Completed
      Site GR30004
      Heraklion, Crete, Greece, 71403
      Completed
      Site DE49002
      Munster, Germany, 48149
      Completed
      Site FR33012
      Albi, France, 81000
      Completed
      Site PL48002
      Lodz, Poland, 93-513
      Completed
      Site ES34003
      Madrid, Spain, 28007
      Completed
      Site FR33005
      Suresnes, France, 92151
      Completed
      Site RU70002
      Moscow, Russian Federation, 105077
      Completed
      Site PL48005
      Warszawa, Poland, 04-141
      Withdrawn
      Site BE32008
      Wilrijk, Belgium, 2610
      Completed
      Site DE49017
      Ulm, Germany, 89075
      Completed
      Site GB44018
      Cardiff, United Kingdom, CF4 7XL
      Completed
      Site ES34008
      Santander, Spain, 39008
      Completed
      Site ES34001
      Madrid, Spain, 28040
      Completed
      Site FR33004
      Plerin, France, 22190
      Completed
      Site DE49008
      Aachen, Germany, 52074
      Completed
      Site DE49001
      Hannover, Germany, 30625
      Completed
      Site PL48004
      Gdańsk, Poland, 80-952
      Completed
      Site GB44014
      Exeter, United Kingdom
      Completed
      Site AT43001
      Vienna, Austria, 1090
      Completed
      Site ES34010
      Madrid, Spain
      Completed
      Site PL48006
      Warszawa, Poland, 02-507
      Completed
      Site IT39008
      Naples, Italy, 80131
      Completed
      Site IT39010
      Pavia, Italy, 27100
      Completed
      Site NO47005
      Drammen, Norway, 3004
      Completed
      Site GB44020
      Northwood, United Kingdom, HA62RN
      Completed
      Site RU70004
      Obninsk, Kaluga, Russian Federation, 24903
      Completed
      Site SE46005
      Kalmar, Sweden, 39185
      Completed
      Site FR33011
      Reims, France, 51056
      Completed
      Site GB44007
      Wirral, United Kingdom, CH63 4JY
      Completed
      Site GR30006
      Athens, Greece, 155 62
      Completed
      Site PL48003
      Krakow, Poland, 31-501
      Completed
      Site FR33002
      Nîmes, France, 30907 cedex 2
      Completed
      Site TR90001
      Ankara, Turkey, 06500
      Completed
      Site DE49015
      Tübingen, Germany, 72076
      Completed
      Site GB44003
      London, United Kingdom, SE1 9RT
      Completed
      Site NL31010
      Nieuwegein, Netherlands, 3435 CM
      Completed
      Site IT39002
      Terni, Italy, 05100
      Completed
      Site FR33008
      Paris, France, 75014
      Completed
      Site DE49018
      Nürtingen, Baden-Württemberg, Germany, 72622
      Completed
      Site ES34005
      Lugo, Lugo, Spain, 27003
      Completed
      Site IT39003
      Milano, Italy, 20100
      Completed
      Site CH41005
      Locarno, Tessin, Switzerland, 6600
      Completed
      Site IT39004
      Rome, Italy, 161
      Completed
      Site RU70005
      St. Petersburg, Russian Federation, 197022
      Completed
      Site NO47001
      Kristiansand, Norway, 4615
      Completed
      Site CZ42004
      Brno, Czech Republic, 656 91
      Completed
      Site IT39001
      Arezzo, Arezzo, Italy, 52100
      Withdrawn
      Site FR33006
      Vandoeuvre les Nancy, France, 54511
      Completed
      Site NL31002
      Amsterdam, Netherlands, 1066 CX
      Completed
      Site GB44015
      Norwich, United Kingdom, NR4 7UY
      Completed
      Site TR90002
      Izmir, Turkey, 35340
      Completed
      Site CH41009
      Zurich, Zurich, Switzerland, CH-8038
      Completed
      Site CZ42003
      Olomouc, Czech Republic, 77520
      Completed
      Site NL31003
      Rotterdam, Netherlands, 3045 PM
      Completed
      Site GR30001
      Heraklion, Crete, Greece, 70013
      Withdrawn
      Site IT39013
      Rome, Italy, 00152
      Completed
      Site ES34009
      Murcia, Spain, 30008
      Completed
      Site GB44010
      Aberdeen, United Kingdom, AB25 2ZN
      Completed
      Site BE32004
      Ottignies, Belgium, 1340
      Completed
      Site CZ42001
      Praha 2, Czech Republic, 12808
      Completed
      Site GB44017
      Swansea, United Kingdom, SA2 8QA
      Completed
      Site ES34002
      Madrid, Spain, 28041
      Completed
      Site FR33013
      Quimper, France, 29000
      Completed
      Site DE49006
      Heidelberg, Germany, 69120
      Completed
      Site BE32002
      Liege, Belgium, 4000
      Completed
      Site FR33003
      Montpellier, France, 34298 cedex 5
      Completed
      Site DE49010
      Bergisch Gladbach, Germany, 51465
      Completed
      Site SE46003
      Solna, Sweden, 171 76
      Completed
      Site SE46002
      Göteborg, Sweden, 413 45
      Completed
      Site ES34004
      Sevilla, Spain, 41013
      Completed
      Site RU70006
      St. Petersburg, Russian Federation, 197758
      Completed
      Site BE32003
      Bonheiden, Belgium, 2820
      Completed
      Site CZ42002
      Plzeň -Lochotín, Czech Republic, 30460
      Completed
      Site DE49003
      Mannheim, Germany, 68167
      Completed
      Site FR33014
      Paris, France, 75014
      Completed
      Site NL31007
      Blaricum, Netherlands, 1261 AN
      Completed
      Site IT39012
      Brescia, Italy, 25126
      Completed
      Site AT43004
      Linz, Austria, 4010
      Completed
      Site GR30003
      Athens, Greece, 14564
      Completed
      Site NL31004
      Hoofddorp, Netherlands, 2134 TM
      Completed
      Site GR30005
      Thessaloniki, Greece, 54007
      Completed
      Site IT39005
      Roma, Italy, 00128
      Withdrawn
      Site GR30002
      Larissa, Greece, 41110

      Frequently Asked Questions

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      Sometimes researchers want participants to keep taking their current treatments during a clinical trial. Other times, you may need to stop your current treatments for a while. If the investigational treatment doesn't work, you can usually go back to your original treatment plan.

      Should I be worried about getting a placebo?

      In cancer clinical trials, a placebo is only used if there is no other treatment for that type of cancer. This helps compare an investigational treatment to the placebo. Placebos are rarely used in cancer trials because the best available treatment, called the “standard of care”, is usually given instead.

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