Study summary

The objectives of this study was to evaluate the safety and efficacy of avacincaptad pegol intravitreal administration in participants with geographic atrophy secondary to age-related macular degeneration (AMD)

Additional Study Details

Phase
Phase 3
Product
avacincaptad pegol
Product
Avacincaptad Pegol
Sham
Type
Interventional
Masking
Double (Participant, Outcomes Assessor)
Enrollment number
448
Show Additional Study Details

Study documents

Scientific Results Summary
Available Language(s): English
Plain Language Summary
Available Language(s): English
Protocol
Available Language(s): English
Statistical Analysis Plan (SAP)
Available Language(s): English

Get more information

Would you like more information about clinical trial sites that are recruiting participants for A Phase 3 Safety and Efficacy Study of Intravitreal Administration of Zimura (Complement C5 Inhibitor)? Contact us by filling out your information to the right and we’ll respond to you.

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  • A parent
  • A patient
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  • Algeria
  • Argentina
  • Armenia
  • Australia
  • Austria
  • Belarus
  • Belgium
  • Bosnia And Herzegovina
  • Brazil
  • Bulgaria
  • Canada
  • Chile
  • China
  • Colombia
  • Croatia
  • Czech Republic
  • Denmark
  • Dominican Republic
  • Egypt
  • Estonia
  • Finland
  • Former Serbia and Montenegro
  • France
  • Georgia
  • Germany
  • Greece
  • Guatemala
  • Hong Kong
  • Hungary
  • Iceland
  • India
  • Indonesia
  • Ireland
  • Israel
  • Italy
  • Japan
  • Jordan
  • Kazakhstan
  • Latvia
  • Lebanon
  • Lithuania
  • Macedonia
  • Malaysia
  • Mexico
  • Montenegro
  • Morocco
  • Netherlands
  • New Zealand
  • Norway
  • Panama
  • Peru
  • Philippines
  • Poland
  • Portugal
  • Puerto Rico
  • Republic of Korea
  • Republic of Moldova
  • Romania
  • Russian Federation
  • Saudi Arabia
  • Serbia
  • Singapore
  • Slovakia
  • Slovenia
  • South Africa
  • Spain
  • Sweden
  • Switzerland
  • Taiwan, Province of China
  • Thailand
  • Turkey
  • Ukraine
  • United Kingdom
  • United States
  • Vietnam

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    Locations

    Contact Us
    Contact Us
    Completed
    Retina-Vitreous Associates Medical Group
    Beverly Hills, California, United States, 90211
    Completed
    Retinal Diagnostic Center
    Campbell, California, United States, 95008
    Completed
    Eye Medical Center of Fresno
    Fresno, California, United States, 93720
    Completed
    Retina Consultants of Orange County
    Fullerton, California, United States, 92835
    Completed
    University of California, San Diego
    La Jolla, California, United States, 92093
    Completed
    Jules Stein Eye Institute/David Geffen School of Medicine
    Los Angeles, California, United States, 90095
    Completed
    Northern California Retina Vitreous Associates
    Mountain View, California, United States, 94040
    Completed
    California Retina Consultants
    Oxnard, California, United States, 93036
    Completed
    Southern California Desert Retina Consultants
    Palm Desert, California, United States, 92211
    Completed
    Doheny Eye Center, UCLA
    Pasadena, California, United States, 91105
    Completed
    Retina Consultants of Southern California
    Redlands, California, United States, 92374
    Completed
    Retinal Consultants Medical Group, Inc.
    Sacramento, California, United States, 95825
    Completed
    Orange County Retinal Medical Group
    Santa Ana, California, United States, 92705
    Completed
    University of Colorado
    Aurora, Colorado, United States, 80045
    Completed
    Retina Consultants of Southern Colorado, P.C.
    Colorado Springs, Colorado, United States, 80909
    Completed
    Colorado Retina Associates
    Lakewood, Colorado, United States, 80228
    Completed
    Connecticut Eye Consultants, P.C.
    Danbury, Connecticut, United States, 06810
    Completed
    Retina Group of New England, PC
    Waterford, Connecticut, United States, 06385
    Completed
    Florida Eye Clinic
    Altamonte Springs, Florida, United States, 32701
    Completed
    Rand Eye Institute
    Deerfield Beach, Florida, United States, 33064
    Completed
    Retina Group of Florida
    Fort Lauderdale, Florida, United States, 33308
    Completed
    National Ophthalmic Research Institute
    Fort Myers, Florida, United States, 33912
    Completed
    Retina Health Center
    Fort Myers, Florida, United States, 33907
    Completed
    VitreoRetinal Associates, P.A.
    Gainesville, Florida, United States, 32607
    Completed
    Florida Eye Associates
    Melbourne, Florida, United States, 32901
    Completed
    University of Miami-Bascom Palmer Eye Institute
    Miami, Florida, United States, 33136
    Completed
    Retina Care Specialists
    Palm Beach Gardens, Florida, United States, 33410
    Completed
    Retina Specialty Institute
    Pensacola, Florida, United States, 32503
    Completed
    Retina Vitreous Associates of Florida
    Saint Petersburg, Florida, United States, 33711
    Completed
    Retina Associates of Sarasota
    Sarasota, Florida, United States, 34233
    Completed
    East Florida Eye Institute
    Stuart, Florida, United States, 34994
    Completed
    Southern Vitreoretinal Associates, PL
    Tallahassee, Florida, United States, 32308
    Completed
    Center for Retina and Macula Disease
    Winter Haven, Florida, United States, 33880
    Completed
    Southeast Retina Center
    Augusta, Georgia, United States, 30909
    Completed
    Georgia Retina, P.C.
    Marietta, Georgia, United States, 30060
    Completed
    Retina Consultants of Hawaii, Inc
    'Aiea, Hawaii, United States, 96701
    Completed
    University Retina and Macula Associates, PC
    Lemont, Illinois, United States, 60439
    Completed
    Illinois Eye Center
    Peoria, Illinois, United States, 61615
    Completed
    Midwest Eye Institute
    Indianapolis, Indiana, United States, 46290
    Completed
    Wolfe Eye Clinic
    West Des Moines, Iowa, United States, 50266
    Completed
    Retina Associates, LLC
    Lenexa, Kansas, United States, 66215
    Completed
    Vitreo Retinal Consultants & Surgeons
    Wichita, Kansas, United States, 67214
    Completed
    Ochsner Medical Center
    New Orleans, Louisiana, United States, 70121
    Completed
    The Retina Care Center
    Baltimore, Maryland, United States, 21209
    Completed
    The Retina Group of Washington
    Chevy Chase, Maryland, United States, 20815
    Completed
    Cumberland Valley Retina Consultants
    Hagerstown, Maryland, United States, 21740
    Completed
    Ophthalmic Consultants of Boston
    Boston, Massachusetts, United States, 02114
    Completed
    Retina Research Institute at New England Retinal Consultants
    Springfield, Massachusetts, United States, 01107
    Completed
    Vitreoretinal Associates, PC
    Worcester, Massachusetts, United States, 01605
    Completed
    UMASS Memorial Eye Center
    Worcester, Massachusetts, United States, 01605
    Completed
    Associated Retinal Consultants, P.C.
    Royal Oak, Michigan, United States, 48073
    Completed
     Retina Center
    Minneapolis, Minnesota, United States, 55404
    Completed
    St. Louis University
    Saint Louis, Missouri, United States, 63110
    Completed
    Retina Consultants of Nevada
    Henderson, Nevada, United States, 89052
    Completed
    Sierra Eye Associates
    Reno, Nevada, United States, 89502
    Completed
    Retina Center of New Jersey, LLC
    Bloomfield, New Jersey, United States, 07003
    Completed
    Long Island Vitreoretinal Consultant
    Great Neck, New York, United States, 11021
    Completed
    Retina Vitreous Surgeons of Central New York, PC
    Liverpool, New York, United States, 13088
    Completed
    Vitreous Retina Macula Consultants of New York (VRMNY)
    New York, New York, United States, 10022
    Completed
    OCLI
    Oceanside, New York, United States, 11572
    Completed
    Retina Associates of Western NY, PC
    Rochester, New York, United States, 14620
    Completed
    Ophthalmic Consultants of the Capital Region
    Troy, New York, United States, 12180
    Completed
    Western Carolina Retinal Associates
    Asheville, North Carolina, United States, 28803
    Completed
    Cincinnati Eye Institute
    Cincinnati, Ohio, United States, 45242
    Completed
    Retina and Vitreous Center of Southern Oregon
    Ashland, OREGON, United States, 97520
    Completed
    Casey Eye Institute
    Portland, OREGON, United States, 97239
    Completed
    EyeHealth Northwest
    Portland, OREGON, United States, 97225
    Completed
    Retina Northwest, PC
    Portland, OREGON, United States, 97221
    Completed
    Mid Atlantic Retina
    Philadelphia, Pennsylvania, United States, 19107
    Completed
    Scheie Eye Institute, University of Pennsylvania
    Philadelphia, Pennsylvania, United States, 19104
    Completed
    Associates in Ophthalmology, Ltd
    West Mifflin, Pennsylvania, United States, 15122
    Completed
    Retina Research of Beaufort, LLC
    Beaufort, South Carolina, United States, 29902
    Completed
    Charleston Neuroscience Institute
    Ladson, South Carolina, United States, 29456
    Completed
    Carolina Macula and Retina
    Mount Pleasant, South Carolina, United States, 29464
    Completed
    Palmetto Retina Center
    West Columbia, South Carolina, United States, 29169
    Completed
    Black Hills Regional Eye Institute
    Rapid City, South Dakota, United States, 57701
    Completed
    Southeastern Retina Associates, PC
    Johnson City, Tennessee, United States, 37604
    Completed
    Southeastern Retina Associates, PC
    Knoxville, Tennessee, United States, 37922
    Completed
    Retina Research Institute of Texas
    Abilene, Texas, United States, 79606
    Completed
    Southwest Retina Specialists
    Amarillo, Texas, United States, 79106
    Completed
    Austin Retina Associates
    Austin, Texas, United States, 78705
    Completed
    Retina Foundation of the Southwest
    Dallas, Texas, United States, 75231
    Completed
    Retina and Vitreous of Texas, PLLC
    Houston, Texas, United States, 77025
    Completed
    Valley Retina Institute
    McAllen, Texas, United States, 78503
    Completed
    Medical Center Ophthalmology Associates
    San Antonio, Texas, United States, 78240
    Completed
    Retina Center of Texas
    Southlake, Texas, United States, 76092
    Completed
    Retinal Consultants of Houston
    The Woodlands, Texas, United States, 77384
    Completed
    Strategic Clinical Research Group
    Willow Park, Texas, United States, 76087
    Completed
    Rocky Mountain Retina Consultants
    Salt Lake City, Utah, United States, 84107
    Completed
    University of Utah, John A. Moran Eye Center
    Salt Lake City, Utah, United States, 84132
    Completed
    Retinal Associates of Utah
    Salt Lake City, Utah, United States, 84107
    Completed
    Wagner Macular & Retina Center
    Norfolk, Virginia, United States, 23502
    Completed
    Retina Institute of Virginia
    Richmond, Virginia, United States, 23235
    Completed
    Vistar Eye Center
    Roanoke, Virginia, United States, 24018
    Completed
    Pacific Northwest Retina
    Bellevue, Washington, United States, 98004
    Completed
    Retina Center NW, PLLC
    Silverdale, Washington, United States, 98383
    Completed
    Instituto Oftalmológico de Buenos Aires
    Buenos Aires, Argentina, C1120AAN
    Completed
    Instituto Oftalmológico de Córdoba
    Córdoba, Argentina, X5000III
    Completed
    Centro Privado de Ojos Romagosa S.A.
    Córdoba, Córdoba, Argentina, X5000AAJ
    Completed
    Centro Privado de Oftalmologia - OFTAR Mendoza SRL
    Mendoza, Argentina, M5500GGK
    Completed
    Centro Medico Micro Diagnostico y Microcirugla Ocular
    Rosario, Argentina, S2000TC
    Completed
    Buenos Aires Macula S.A.
    Buenos Aires, CABA, Argentina, Cl061AAE
    Completed
    Centro Oftalmológico Dr. Charles SA
    Buenos Aires, CABA, Argentina, C1116ABA
    Completed
    Centro de Diagnóstico y Cirugía Ocular "Oftalmólogos Especialistas"
    Rosario, Santa Fe, Argentina, S2000ANJ
    Completed
    Centro Médico Grupo Laser Visión
    Rosario, Santa Fe, Argentina, CP2000
    Completed
    Royal Victorian Eye & Ear Hospital
    East Melbourne, Australia, 3002
    Completed
    Sydney Eye Hospital
    Sydney, NSW, Australia, 2000
    Completed
    Sydney Retina Clinic and Day Surgery
    Sydney, NSW, Australia, 2000
    Completed
    Medizinische Universitaet Graz - Augenklinik
    Graz, Austria, 8036
    Completed
    Medizinische Universitaet Innsbruck - Universitaetsklinik fuer Augenheilkunde und Optometrie
    Innsbruck, Austria, 6020
    Completed
    Hanush Hospital
    Vienna, Austria, 1140
    Completed
    Medical University of Vienna
    Vienna, Austria, 1090
    Completed
    CHU Brugmann
    Brussels, Belgium
    Completed
    Centro de Ensino e Pesquisa do Instituto da Visao (CEPIV)
    Belo Horizonte, Brazil, 30330
    Completed
    IPEPO - Instituto da visão
    São Paulo, Brazil, 04038-032
    Completed
    Hospital Sao Paulo - UNIFESP
    Vila Clementino, Brazil, 04023-062
    Completed
    Retina Centre of Ottawa
    Ottawa, Canada, K2B 7E9
    Completed
    Calgary Retina Consultants
    Calgary, Alberta, Canada, T2H 0C8
    Completed
    UBC/VGH Eye Care Center
    Vancouver, British Columbia, Canada, V5Z3N9
    Completed
    Canadian Centre for Advanced Eye Therapeutics Inc.
    Mississauga, ON, Canada, L4W 1W9
    Completed
    St.Joseph's Health Care London
    London, Ontario, Canada, N6A4V2
    Completed
    University of Ottawa Eye Institute
    Ottawa, Ontario, Canada, K1H8L6
    Completed
    University Health Network
    Toronto, Ontario, Canada, M5T 2S8
    Completed
    Fundacion OJlalmologica Nacional - FUNDONAL
    Bogotá, Colombia, 110311
    Completed
    Clinica De Oftalmologia Sandiego
    Medellín, Antioquia, Colombia, 050016
    Completed
    Clinical hospital Center Osijek
    Osijek, Croatia, 31000
    Completed
    Axon Clinical s.r.o.
    Prague, Smichov, Czech Republic, 150 00
    Completed
    Dr Kai Noor Silmakabinet
    Tallin, Estonia, 11412
    Completed
    Tartu University Hospital
    Tartu, Estonia, 50406
    Completed
    CHU de Bordeaux – Hopital Pellegrin
    Bordeaux, France, 33000
    Completed
    Hopital Intercommunal
    Créteil, France, 94010
    Completed
    CHU Bocage
    Dijon, France, 21079
    Completed
    Hopital de la Croix Rousse
    Lyon, France, 69004
    Completed
    Centre d'ophtalmologie Rabelais
    Lyon, France, 69002
    Completed
    Centre Paradis Monticelli
    Marseille, France, 13008
    Completed
    CHU de Nantes
    Nantes, France, 44043
    Completed
    Centre Ophtalmologique d'Imagerie et de Laser
    Paris, France, 75015
    Completed
    Centre d'exploration ophtalmologique de l'Odeon
    Paris, France, 75006
    Completed
    Hôpital Lariboisière
    Paris, France, 75010
    Completed
    Fondation Alolphe de Rotschild
    Paris, France, 75019
    Completed
    Centre St Exupery
    Saint-Cyr-sur-Loire, France, 37540
    Completed
    Centre Pole Vision Val d'Ouest
    Écully, France, 69130
    Completed
    RWTH Aachen University
    Aachen, Germany, 52074
    Completed
    University of Göttingen
    Göttingen, Germany, 37075
    Completed
    Universitätsklinikum Hamburg Eppendorf Klinik und Poliklinik für Augenheilkunde Studienzentrum
    Hamburg, Germany, 20251
    Completed
    University Eye Hospital, MHH
    Hanover, Germany, 30625
    Completed
    Augenklinik University Hospital Cologne
    Köln, Germany, 50937
    Completed
    University clinic Leipzig AÖR
    Leipzig, Germany, 04103
    Completed
    Universitätsklinikum Schleswig-Holstein
    Lübeck, Germany, 23538
    Completed
    Universitätsmedizin der Johannes Gutenberg-Universität Mainz
    Mainz, Germany, 55131
    Completed
    Clinic Rechts der Isar
    Munich, Germany, 81675
    Completed
    Ludwig-Maximilians-University Munich
    Munich, Germany, 80336
    Completed
    Universitätsklinikum Münster
    Münster, Germany, 48149
    Completed
    Augenzentrum am St. Franziskus-Hospital
    Münster, Germany, 48145
    Completed
    Universitäts-Augenklinik
    Tübingen, Germany, 72076
    Completed
    Budapest Retina Associates
    Budapest, Hungary, 1133
    Completed
    Bajcsy Zsilinszky Kórház - Szemészet
    Budapest, Hungary, 1106
    Completed
    Semmelweis University, Dept of Ophthalmology
    Budapest, Hungary, H-1085
    Completed
    Hungarian Military Hospital Center
    Budapest, Hungary, 1068
    Completed
    Debrecen University Clinical Center, Dept of Ophthalmology
    Debrecen, Hungary, H-4032
    Completed
    Szabolcs-Szatmar-Bereg County Hospital and University Teaching Hospital
    Nyiregyhaza, Hungary, 4400
    Completed
    Ganglion Medical Center
    Pécs, Hungary, H-7621
    Completed
    Szegedi Tudomanyegyetem Szent-Gyorgyi Albert Klinikai Kozpont
    Szeged, Hungary, H-6720
    Completed
    Barzilai Medical Center
    Ashkelon, Israel, 7830604
    Completed
    Shamir Medical Center
    Be'er Ya'aqov, Israel, 70300
    Completed
    Rambam Medical Centre
    Haifa, Israel, 3109601
    Completed
    Carmel Medical Center
    Haifa, Israel, 3436212
    Completed
    Edith Wolfson Medical Center
    Holon, Israel, 5822012
    Completed
    Hadassah University Hospital
    Jerusalem, Israel, 91120
    Completed
    Department of Ophthalmology, Rabin Medical Center
    Petah tikva, Israel, 49100
    Completed
    Kaplan Medical Center
    Reẖovot, Israel, 76100
    Completed
    Sourasky Medical Center
    Tel Aviv, Israel, 6423906
    Completed
    Ospedali Riuniti di Ancona
    Ancona, Italy, 60126
    Completed
    A.O.U. Policlinico Sant'Orsola-Malpighi
    Bologna, Italy, 40138
    Completed
    Ospedale Clinicizzato Universita di Chieti "Ss Annunziata"
    Chieti, Italy, 66100
    Completed
    Nuovo Arcispedale Sant' Anna (A.O.U. di Ferrara)
    Ferrara, Italy, 44124
    Completed
    Azienda Ospedaliera Universitaria Careggi
    Florence, Italy, 50134
    Completed
    IRCCS Ospedale San Raffaele
    Milan, Italy, 20132
    Completed
    Ospedale Luigi Sacco
    Milan, Italy, 20157
    Completed
    Ospedale Maggiore Policlinico Milano
    Milan, Italy, 20122
    Completed
    AOU Universita degli Studi della Campania Luigi Vanvitelli UOC Oculistica
    Naples, Italy, 80131
    Completed
    Azienda Ospedaliera di Padova Unità Operativa Complessa di Clinica Oculistica
    Padova, Italy, 35128
    Completed
    University of Pisa
    Pisa, Italy, 56126
    Completed
    Fondazione GB Bietti IRCCS
    Roma, Italy, 00198
    Completed
    Fondazione PTV
    Roma, Italy, 00133
    Completed
    Azienda Sanitaria Universitaria Integrata
    Udine, Italy, 33100
    Completed
    Pauls Stradinis Clinical University Hospital
    Riga, Latvia, LV-1002
    Completed
    Klinika Okulistyczna OFT ALMIKA Sp. z o. o.
    Bydgoszcz, Poland, 85-631
    Completed
    Caminomed
    Tarnowskie Góry, Poland, 42-600
    Completed
    Uniwersytecki Szpital Kliniczny im. Jana Mikulicza-Radeckiego
    Wrocław, Poland, 50-556
    Completed
    Medical Center Julianów
    Łódź, Poland, 91-485
    Completed
    Clinica de Oftalmologia Barraquer
    Barcelona, Spain, 08021
    Completed
    Institut Catala de Retina
    Barcelona, Spain, 08022
    Completed
    VOR - Hospital General de Catalunya
    Barcelona, Spain, 08195
    Completed
    Institut de la Macula
    Barcelona, Spain, 08022
    Completed
    Instituto Clinico Quirurgico de Oftalmologia
    Bilbao, Spain, 48010
    Completed
    Hospital La Arruzafa
    Córdoba, Spain, CP 14012
    Completed
    H.U. Puerta de Hierro-Majadahonda
    Majadahonda, Spain, 28222
    Completed
    Clinica Universidad de Navarra
    Pamplona, Spain, 31008
    Completed
    Instituto Oftalmologico Gomez-Ulla
    Santiago De Compostela, Spain, 15706
    Completed
    IMED Servicio Oftalmología
    Valencia, Spain, 46100
    Completed
    Rio Hortega University Hospital
    Valladolid, Spain, 47012
    Completed
    Hull University Teaching Hospitals NHS Trust
    Hull, United Kingdom, HU3 2JZ
    Completed
    Hospital Clínico Universitario "Lozano Blesa"
    Zaragoza, Spain, 50009
    Completed
    University of Bonn
    Bonn, Germany

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