Study summary

The purpose of this study is to evaluate the safety and efficacy of avacincaptad pegol intravitreal injection compared to Sham in participants with autosomal recessive Stargardt disease 1 (STGD1).

Additional Study Details

Phase
Phase 2
Product
  • avacincaptad pegol
  • Sham
  • Type
    Interventional
    Masking
    Triple (Participant, Investigator, Outcomes Assessor)
    Enrollment number
    121
    Show Additional Study Details

    Get more information

    Would you like more information about clinical trial sites that are recruiting participants for Zimura Compared to Sham in Patients with Autosomal Recessive Stargardt Disease (STGD1)? Contact us by filling out your information to the right and we’ll respond to you.

    • A patient
    • A caregiver
    • A parent
    • A healthcare provider
    • A patient advocate
    • Algeria
    • Argentina
    • Armenia
    • Australia
    • Austria
    • Belarus
    • Belgium
    • Bosnia And Herzegovina
    • Brazil
    • Bulgaria
    • Canada
    • Chile
    • China
    • Colombia
    • Croatia
    • Czech Republic
    • Denmark
    • Dominican Republic
    • Egypt
    • Estonia
    • Finland
    • Former Serbia and Montenegro
    • France
    • Georgia
    • Germany
    • Greece
    • Guatemala
    • Hong Kong
    • Hungary
    • Iceland
    • India
    • Indonesia
    • Ireland
    • Israel
    • Italy
    • Japan
    • Jordan
    • Kazakhstan
    • Latvia
    • Lebanon
    • Lithuania
    • Macedonia
    • Malaysia
    • Mexico
    • Montenegro
    • Morocco
    • Netherlands
    • New Zealand
    • Norway
    • Panama
    • Peru
    • Philippines
    • Poland
    • Portugal
    • Puerto Rico
    • Republic of Korea
    • Republic of Moldova
    • Romania
    • Russian Federation
    • Saudi Arabia
    • Serbia
    • Singapore
    • Slovakia
    • Slovenia
    • South Africa
    • Spain
    • Sweden
    • Switzerland
    • Taiwan, Province of China
    • Thailand
    • Turkey
    • Ukraine
    • United Kingdom
    • United States
    • Vietnam

    By clicking ["Continue/Submit"], you agree that Astellas may contact you by email with information to help you connect with clinical trial sites. While we can connect you to clinical trial sites, we cannot answer questions about any investigational therapy through email. Your consent to receiving emails is not a requirement to participate in a clinical trial or study. For more information, including how to unsubscribe at any time, see our Privacy Notice & Cookies Policy.

      Locations

      Contact Us
      Contact Us
      Active, not recruiting
      Retinal Research Institute
      Phoenix, Arizona, United States, 85053
      Completed
      Jules Stein Eye Institute/ David Geffen School of Medicine
      Los Angeles, California, United States, 90095
      Completed
      VitreoRetinal Associates
      Gainesville, Florida, United States, 32607
      Completed
      Wilmer Eye Institute, Johns Hopkins
      Baltimore, Maryland, United States, 21287
      Completed
      Ophthalmic Consultants of Boston
      Boston, Massachusetts, United States, 02114
      Completed
      University of Michigan/Kellogg Eye Center
      Ann Arbor, Michigan, United States, 48105
      Completed
      The Retina Center
      Minneapolis, Minnesota, United States, 55404
      Active, not recruiting
      Casey Eye Institute/Oregon Health & Science University
      Portland, OREGON, United States, 97239
      Active, not recruiting
      Wills Eye Hospital/Mid Atlantic Retina
      Philadelphia, Pennsylvania, United States, 19107
      Completed
      UPMC Eye Center
      Pittsburgh, Pennsylvania, United States, 15213
      Completed
      Palmetto Retina Center
      West Columbia, South Carolina, United States, 29169
      Active, not recruiting
      Austin Retina Associates
      Austin, Texas, United States, 78705
      Completed
      Retina Foundation of the Southwest
      Dallas, Texas, United States, 75231
      Completed
      Strategic Clinical Research Group
      Willow Park, Texas, United States, 76087
      Completed
      University of Utah John A. Moran Eye Center
      Salt Lake City, Utah, United States, 84132
      Withdrawn
      Montreal Children's Hospital
      Montréal, Canada, H4A 3J1
      Completed
      Creteil University Eye Clinic University Paris EST
      Créteil, France, 94010
      Completed
      Centre ophtalmologique des Quinzes Vingts
      Paris, France, 75012
      Completed
      Hopital de la Croix-Rousse
      Lyon, Rhone-Alpes, France, 69004
      Completed
      University of Bonn
      Bonn, Germany, 53127
      Completed
      Augenklinik der LMU München
      München, Germany, 80336
      Completed
      University of Tuebingen
      Tübingen, Germany, 72076
      Completed
      Budapest Retina Institute
      Budapest, Hungary, 1133
      Completed
      Semmelweis Egyetem
      Budapest, Hungary, H-1083
      Completed
      University of Debrecen DE KK Szemészeti Klinika
      Debrecen, Hungary, 4032
      Completed
      Ganglion Medical Center
      Pécs, Hungary, 7621
      Completed
      Szegedi Tudomanyegyetem, Szent-Gyorgyi Albert Klinikai Kozpont, Szemeszeti Klinika
      Szeged, Hungary, 6720
      Completed
      Rambam Health Care Campus
      Haifa, Israel, 3109601
      Completed
      Hadassah University Hospital
      Jerusalem, Israel, 9112001
      Completed
      Rabin Medical Center, Beilinson campus
      Petah tikva, Israel, 4941492
      Completed
      Kaplan Medical Center
      Reẖovot, Israel, 7610001
      Completed
      Tel-Aviv Sourasky Medical Center, Ichilov Hospital
      Tel Aviv, Israel, 6423906
      Completed
      AOU Policlinico Sant’Orsola Malpighi, U.O. Oftalmologia,
      Bologna, Italy, 40138
      Completed
      Azienda Ospedaliera Universitaria Careggi
      Florence, Italy, 50121
      Completed
      Ospedale San Raffaele
      Milano, Italy, 20132
      Completed
      University of Campania Luigi Vanvitelli Eye Clinic
      Naples, Italy, 80131
      Completed
      Fondazione Policlinico Tor Vergata, UOSD Patologie Retiniche
      Rome, Italy, 00133
      Completed
      Institut de la Macula
      Barcelona, Barcelona, Spain, 08022
      Completed
      Princess Alexandra Eye Pavillion
      Edinburgh, United Kingdom, EH3 9HA
      Completed
      Moorfields Eye Hospital
      London, United Kingdom, EC1V 2PD
      Active, not recruiting
      Retina Specialty Institute
      Pensacola, Florida, United States, 32503
      Completed
      Retina Center of NJ, LLC.
      Bloomfield, NJ, United States, 07003
      Withdrawn
      Retina Consultants of Texas
      Bellaire, Texas, United States, 77401

      Frequently Asked Questions

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      Should I be worried about getting a placebo?

      In cancer clinical trials, a placebo is only used if there is no other treatment for that type of cancer. This helps compare an investigational treatment to the placebo. Placebos are rarely used in cancer trials because the best available treatment, called the “standard of care”, is usually given instead.

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