Study summary

This is a phase 2 study to evaluate the efficacy of single-agent erlotinib versus oral etoposide in patients with recurrent or refractory pediatric ependymoma.

Additional Study Details

Phase
2
Product
  • erlotinib
  • etoposide
  • Type
    Interventional
    Masking
    None (Open Label)
    Enrollment number
    25
    Show Additional Study Details

    Study documents

    Scientific Results Summary
    Available Language(s): English
    Plain Language Summary
    Available Language(s): English

    Get more information

    Would you like more information about clinical trial sites that are recruiting participants for Erlotinib versus oral etoposide in patients with recurrent or refractory pediatric ependymoma? Contact us by filling out your information to the right and we’ll respond to you.

    • A patient
    • A caregiver
    • A parent
    • A healthcare provider
    • A patient advocate
    • Algeria
    • Argentina
    • Armenia
    • Australia
    • Austria
    • Belarus
    • Belgium
    • Bosnia And Herzegovina
    • Brazil
    • Bulgaria
    • Canada
    • Chile
    • China
    • Colombia
    • Croatia
    • Czech Republic
    • Denmark
    • Dominican Republic
    • Egypt
    • Estonia
    • Finland
    • Former Serbia and Montenegro
    • France
    • Georgia
    • Germany
    • Greece
    • Guatemala
    • Hong Kong
    • Hungary
    • Iceland
    • India
    • Indonesia
    • Ireland
    • Israel
    • Italy
    • Japan
    • Jordan
    • Kazakhstan
    • Latvia
    • Lebanon
    • Lithuania
    • Macedonia
    • Malaysia
    • Mexico
    • Montenegro
    • Morocco
    • Netherlands
    • New Zealand
    • Norway
    • Panama
    • Peru
    • Philippines
    • Poland
    • Portugal
    • Puerto Rico
    • Republic of Korea
    • Republic of Moldova
    • Romania
    • Russian Federation
    • Saudi Arabia
    • Serbia
    • Singapore
    • Slovakia
    • Slovenia
    • South Africa
    • Spain
    • Sweden
    • Switzerland
    • Taiwan, Province of China
    • Thailand
    • Turkey
    • Ukraine
    • United Kingdom
    • United States
    • Vietnam

    By clicking ["Continue/Submit"], you agree that Astellas may contact you by email with information to help you connect with clinical trial sites. While we can connect you to clinical trial sites, we cannot answer questions about any investigational therapy through email. Your consent to receiving emails is not a requirement to participate in a clinical trial or study. For more information, including how to unsubscribe at any time, see our Privacy Notice & Cookies Policy.

      Locations

      Contact Us
      Contact Us
      Terminated
      Steven D Hassenfeld Children’s Center – New York University
      New York, New York, United States, 10016
      Terminated
      University of Wisconsin Pediatric Hematology/Oncology Department
      Madison, WI, United States, 53705-2275
      Terminated
      Stanford University and Lucile Packard Children’s Hospital
      Palo Alto, California, United States, 94304
      Terminated
      Royal Manchester Children's Hospital Ward 84
      Manchester, United Kingdom, M13 9W2
      Terminated
      Birmingham Children's Hospital
      Birmingham, United Kingdom, B4 6NH
      Terminated
      Royal Marsden Hospital
      Sutton, United Kingdom, SM2 5PT
      Terminated
      Children's Medical Center, Dallas Center for Cancer and Blood Disorders
      Dallas, TX, United States, 75235
      Terminated
      University of Alabama at Birmingham Dept. of Pediatric-Hematology/Oncology
      Birmingham, AL, United States, 35233
      Terminated
      Children’s and Women’s Health Center of BC Division of Hematology/ Oncology/ BMT
      Vancouver, British Columbia, Canada, V6H 3V4
      Withdrawn
      University of Florida Shands Children's Hospital
      Gainesville, FL, United States, 32610-0296
      Terminated
      Strollery Children's Hospital Division of Hematology/Oncology
      Edmonton, Alberta, Canada, T6G 2B7
      Terminated
      Paediatric Oncology and Haematology Offices
      Leeds, United Kingdom, LS1 3EX
      Terminated
      Penn State Hershey Children's Hospital
      Hershey, PA, United States, 17110
      Withdrawn
      Children's Memorial Medical Hospital
      Chicago, IL, United States, 60614
      Terminated
      University of Miami
      Miami, FL, United States, 33136
      Terminated
      Royal Hospital for Sick Children
      Glasgow, United Kingdom, G3 8SJ
      Terminated
      Oregon Health & Sciences University Doembecher Children's Hospital
      Portland, OR, United States, 97124
      Terminated
      Center for Cancer and Blood Disorders-Phoenix Children's Hospital
      Phoenix, Arizona, United States, 85016
      Terminated
      Hospital for Sick Children
      Toronto, ON, Canada, M5G 1X8
      Terminated
      Alder Hey Children’s NHS Foundation Trust Department of Oncology
      Liverpool, United Kingdom, L12 1AP
      Terminated
      Amplatz Children's Hospital University of Minnesota Medical Center- Pediatric Hematology Oncology
      Minneapolis, MN, United States, 55455
      Terminated
      University of Nottingham Children's Brain Tumour Research Centre
      Nottingham, United Kingdom, NG7 2UH
      Terminated
      Children's National Medical Center - D.C. Center for Cancer and Blood Disorders
      Washington, DC, United States, 20010
      Terminated
      Emory University Children's Healthcare of Atlanta Aflac Cancer Center & Blood Disorders
      Atlanta, GA, United States, 30322
      Terminated
      Children's Hospital of Orange County (CHOC)
      Orange, CA, United States, 92868
      Terminated
      Columbia University Children's Hospital of New York Presbyterian Child & Adolescent Oncology Center
      New York, NY, United States, 10032
      Terminated
      Children's Hospital of Pittsburgh of UPMC
      Pittsburgh, PA, United States, 15224
      Terminated
      Dana-Farber Cancer Institute Department of Pediatric Neuro-oncology
      Boston, MA, United States, 02115
      Terminated
      Johns Hopkins University School of Medicine
      Baltimore, MD, United States, 21287
      Terminated
      Children's Hospital Center for Cancer and Blood Disorders
      Aurora, CO, United States, 80045

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      Should I be worried about getting a placebo?

      In cancer clinical trials, a placebo is only used if there is no other treatment for that type of cancer. This helps compare an investigational treatment to the placebo. Placebos are rarely used in cancer trials because the best available treatment, called the “standard of care”, is usually given instead.

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